Transfemme

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What does transfemme mean?

What does Transfemme mean?

What Does Transfemme Mean?

Transfemme is derived from the French word Femme, meaning woman and the English word Trans, taken from the word transgender, it was coined by the late Dr. Robert Archer of Incline Village, Nevada, in November of 2002, for Avalon Essentials, LLC to brand their Transfemme male-to-female breast enlargement pills and cream. 

At the time, the transgender movement was much smaller, being transgender was still very much in the closet, and transgender people did not have the rights or the acceptance they do today. 

With the recognition and more mainstream acceptance of transgender and Transfemme individuals, many words and definitions have been coined and movements created around gender expression, gender fluidity and gender equality law. 

The Transgender community has had an all-time high of visibility and representation under the past administration and the coming out of Caitlin Jenner.  Caitlin Jenner also fits the definition of what does Transfemme mean; she fits the definition of a Transfemme individual perfectly. The second part of the word transfemme is the french word Femme, which is used in English-speaking countries as a lesbian identity that was created in the USA in the 1950s. Femme is a term used to distinguish a feminine lesbian and bisexual woman from the masculine butch type lesbians. A transfemme is a similar word for the male to the female equivalent of the word femme for lesbians.

What is the Definition of Transfemme?

Transfemme is a word that is not only a trademark but is also used by the general public to describe a biological male who is feminine, or who is or is becoming a female or more feminine.  Other people are using the word Transfeminine to describe a Transfemme individual or Forced Feminization.  We can see why the words trans and femme were combined to reference a male-to-female person and why it is used as Avalon Essentials, LLC’s brand name for the Transfemme male-to-female breast enlargement cream and pills. What does Transfeminism mean?   Transfeminism is a social movement. The Transfeminism Anthology Project was founded in 2000.  It is thought that Diana Courvant coined the word transfeminism as early as 1992. Transfeminists seek to merge their own transgender concerns with those of feminism, arguing that all women deserve the equal rights men enjoy. The transfeminist movement is not without controvers,y as many feminists do not see transwomen as real women.

Transfemme Meaning & Origin

Transfemme is derived from the French word Femme, meaning woman and the English word Trans, taken from the word transgender.

The term Transfemme serves not only as a trademarked brand by Avalon Essentials, LLC but also as a widely adopted term describing biological males who express femininity or are transitioning to female. While some use Transfeminine interchangeably, it’s important to note that Transfemme specifically combines:

  1. “Trans” (from “transgender”)

  2. “Femme” (French for “woman”)

Who coined the word “Transfemme”?

The late Dr. Robert Archer of Incline Village, Nevada, created the term “Transfemme” in November 2002 for Avalon Essentials, LLC to brand their male-to-female breast enlargement pills and cream.

The Evolution of Transgender Visibility

In 2002, the transgender movement operated on a much smaller scale, with limited rights and societal acceptance forcing many transgender individuals to stay closeted. Today, society dramatically embraces transgender identities, driving the creation of new language about gender expression, fluidity, and equality laws.

In English-speaking cultures, “femme” became a lesbian identity in the 1950s, describing feminine lesbian and bisexual women (contrasting with “butch” lesbians). Similarly, “transfemme” represents the male-to-female equivalent of this term.

Transgender Representation Today

  • The transgender community reached unprecedented visibility under recent U.S. administrations.

  • Public figures like Caitlyn Jenner (a quintessential Trans individual) helped normalize transgender identities.

The Transgender community has had an all-time high of visibility and representation under the past administration and the coming out of Caitlin Jenner. Caitlin Jenner also fits the definition of what does Transfemme mean, she fits the definition of a Transfemme individual perfectly. The second part of the word transfemme is the french word Femme, it is used in English speaking countries as a lesbian identity that was created in the USA in the 1950s. Femme is a term used to distinguish a feminine lesbian and bisexual women from the masculine butch type lesbians. A transfemme is a similar word for the male to the female equivalent of the word femme for lesbians.

What Does Transfemme Mean?

The term Transfemme® serves dual purposes: as a trademark of Avalon Essentials, LLC and as a common descriptor for feminine-identifying biological males or those transitioning to female. Many people now use Transfeminine interchangeably with Transfemme, including in discussions of forced feminization. This combination of “trans” and “femme” perfectly describes male-to-female transitions, which explains why Avalon Essentials invented this word and chose it for their transgender breast enhancement products.

Understanding Transfeminism

https://en.wikipedia.org/wiki/Transfeminism

The Transfeminism Movement emerged when Diana Courvant first coined the term in 1992. Activists launched the Transfeminism Anthology Project in 2000 to advance its principles. Transfeminists champion gender equality by integrating transgender rights with feminist causes, demanding equal rights for all women. However, this movement faces opposition from feminists who contest the inclusion of trans women in women’s spaces.

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Understanding Gender Dysphoria for Male-to-Female Transgender Individuals

Understanding MTF Gender Dysphoria and How to Manage It

Gender dysphoria is a deeply personal experience that many male-to-female (MTF) transgender individuals face. It refers to the emotional distress caused by a mismatch between one’s gender identity and the sex assigned at birth. For many trans women, this can manifest as anxiety, depression, social withdrawal, or a profound sense of being out of alignment with oneself.

In this guide, we’ll explore what gender dysphoria is, how it affects MTF individuals, and how you can take empowering steps—both emotionally and physically—to feel more at home in your body and identity.

What Is Gender Dysphoria?

MTF gender dysphoria can range from discomfort with certain body features to intense distress related to one’s physical appearance and social role. According to the DSM-5, gender dysphoria is diagnosed based on a strong, persistent incongruence between one’s experienced gender and assigned sex, often paired with a desire to change primary or secondary sex characteristics. Every journey is different. Some individuals experience mild dissatisfaction, while others may feel deeply disconnected from their appearance, name, or how others perceive them.

How Does Gender Dysphoria Affect MTF or Male to Female Transgender Individuals?

If you’re a trans woman experiencing gender dysphoria, know that you’re not alone. The emotional toll can impact every area of life—from mental health to relationships. Common experiences may include:

  • Discomfort with male physical features or anatomy
  • Guilt, shame, or confusion surrounding gender identity
  • Fear of rejection, discrimination, or being misgendered
  • Isolation or anxiety in social situations
  • Concerns about acceptance from family and friends
  • Wishing you could fully embrace a female identity

The good news is: you can take steps to feel more aligned, confident, and empowered. In order to be diagnosed with gender dysphoria, an individual must meet certain criteria outlined in the Diagnostic and Statistical Manual of Mental Disorders (DSM-5). These include a marked incongruence between one’s experienced/expressed gender and primary and/or secondary sex characteristics, a strong desire to be rid of those sex characteristics or have other physical features that match one’s experienced gender, and a strong desire for the primary or secondary sex characteristics of the other gender.

What You Can Do to Alleviate Gender Dysphoria?

There is no “one-size-fits-all” approach to overcoming gender dysphoria, but there are proven ways to ease its impact and move closer to your authentic self.

At Transfemme®, we’ve supported thousands of male, crossdressers, transgender women since the 1990s with natural, non-invasive feminization products designed to help you feel more confident, comfortable, and truly you.

Here’s how to get started:

1. Start with Support

Reach out to supportive friends, online communities, or a licensed therapist experienced in transgender issues. Being heard and validated is a powerful first step.

2. Take Steps Toward Transition

Whether socially (changing name/pronouns) or medically (hormone therapy, surgeries), transitioning can bring significant relief. Every step counts—and it’s okay to go at your own pace.

3. Embrace Feminine Self-Care

Explore makeup, hairstyles, or skincare routines that make you feel more aligned with your identity. Small changes, like growing your hair or dressing in women’s clothing, can make a big difference in confidence and self-image.

4. Build a Supportive Environment

Surround yourself with people and places that affirm your journey. If needed, consider relocating to a city or state more welcoming of transgender individuals.

5. Consider Feminization Products

Natural feminization is possible—and Transfemme offers scientifically formulated support that thousands of customers trust:

6. Explore Cosmetic Enhancements (Optional)

Some choose subtle cosmetic procedures—like lip fillers, nose refinement, or tracheal shave—to enhance their feminine features. If this feels right for you, consult licensed professionals.

7. Find Joy in Female Activities

Connect with other women through shared interests: beauty salons, clothing shopping, or simply chatting over coffee. Building friendships with women can enrich your experience of femininity.

Final Thoughts

Living with gender dysphoria can be incredibly difficult—but there is hope, support, and a path forward. Whether you’re just beginning or continuing your MTF transformation, know that your journey is valid and worthy of love and care.

At Transfemme®, we’ve helped thousands of male, crossdressers, sissy, and transgender women embrace their feminine identity with safe, natural feminization support since 1996—when very few dared to speak openly. We understand your challenges because we’ve walked this road with others before you.

✨ You deserve to feel beautiful and aligned with your true self.
If you’re ready to take the next step, we’re here to help.

📞 Call us at 877-552-3033
💬 Or chat with us and fill out our personalized questionnaire to begin your feminization journey today.

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MTF Surgery

Male-to-female surgery, or gender reassignment surgery, is a procedure that changes the male reproductive organs into female reproductive organs. This surgery is often performed on transgender women, people who identify as women but were born with male reproductive organs and male chromosomes, or intersex chromosomes. The goal of the surgery is to create a body that matches the person’s internal gender identity.

There are several different types of MTF surgery that can be performed to change the male reproductive organs into female reproductive organs. The most common type of surgery is called vaginoplasty. This surgery creates a vagina by taking skin from the penis and scrotum and using it to form the new vaginal walls. bowel vaginoplasty is a surgery in which a section of bowel is used to create a vagina. This surgery is most commonly used to treat vaginal agenesis (a birth defect in which the vagina does not form), to create a vagina in people who have undergone male-to-female gender affirmation surgery, or to fix a failed vaginal reconstruction. The clitoris is also usually recreated using tissue from the penis.
Other surgeries that may be performed include breast augmentation, liposuction, Adam’s Apple reduction, vocal surgery, and hair removal.
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transfemme breast enlargement pill
What is Gender Reassignment Surgery?
Gender reassignment surgery, or sex reassignment surgery, is a surgical procedure that changes the genitals of someone born with a reproductive system that doesn’t match their gender identity. This type of surgery is often used to treat gender dysphoria. Gender dysphoria is a condition where someone feels like their gender identity doesn’t match the gender they were assigned at birth.
There are both pros and cons to undergoing gender reassignment surgery. Some pros include a greater sense of self-esteem and happiness, improved mental health, and increased satisfaction with life. Some cons include the cost of surgery, the risk of complications, and the fact that not everyone is eligible for surgery.
Gender reassignment surgery is a major decision, so it’s important to weigh all the pros and cons before making a final decision and being 100% sure that you are ready to live your life as a woman. If you’re considering surgery, be sure to talk to your therapist and doctor about your options and what to expect.
Male to female (MTF surgery) is a major operation that requires extensive healing time. Most people require at least six weeks of recovery time before they can resume normal activities. There are also some risks associated with the surgery, including infection, bleeding, and scarring. However, most people who undergo gender reassignment surgery report feeling much more comfortable in their own skin after the operation. A certain percentage of Sex Reassignment Patients want to transition back to being male. We have also had customers tell us they have complications such as pain, leaving them unable to have sex, and unpleasant odors that will not go away (presumably, this is caused by the bowel resection method.

Most of our Transfemme® customers are happy to live as Tgirls without resorting to drastic and dangerous surgery.

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How Can A Man Grow Female Breasts Without Hormones?

A world-famous product on the market is causing a stir among transgender women and cross-dressers – Transfemme®, a breast enlargement cream, and Transfemme® capsules that help men grow female breasts without hormones or surgery.

“I was skeptical at first, but I decided to give it a try,” said Jerry, a 38-year-old man who has been using Transfemme for two months. “I’m happy to say that my breasts have definitely grown bigger, and I’ve had no side effects.” 

Transfemme is made with all-natural ingredients, including Pueraria Mirifica extract, an herb found in Thailand that has been used for centuries to promote breast growth. 

Pueraria Mirifica and Placenta are two of the key ingredients in Transfemme®, and it’s what makes our product so effective,” said Elizabeth, the CEO of Avalon Essentials, the company that makes Transfemme® pills. “Not only does it help promote breast growth, but it also helps improve skin elasticity and decreases the appearance of wrinkles.”

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For best results, Elizabeth recommends using Transfemme® cream twice daily – once in the morning and once at night. Within four to six weeks, she says, you should start seeing results.
The reviews for Transfemme® have been overwhelmingly positive. “This stuff actually works!” wrote one customer on Helpful Crowd. “I’ve been using it for about two months now, and my breasts have grown a full cup size.”
There is a powerful product on the market that is helping men grow female breasts without the use of drugs or surgery, called Transfemme®; this product uses all-natural protomorphogen therapy ingredients to promote breast growth in men.
Since its release, Transfemme has become incredibly popular among men who want to grow breasts. The product was invented in1996 so transwomen and men can feel confident that they are making a safe and effective purchase.

Transfemme is made up of a blend of glandulars, kelp, and frequencies that lead to dramatic breast growth in men. The product is taken orally, and most men see results within just a few weeks. 

 

In addition to promoting breast growth, Transfemme also helps to improve overall feminizing hormone balance in the body. This can lead to many other health benefits, such as improved happiness, well-being, better sleep quality, and reduced stress levels.

 

If you’re interested in growing female breasts without using drugs or surgery, then be sure to check out Transfemme® pills, and Transfemme® Cream.

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What are the benefits of feminization?

There is no shame in questioning your gender identity or taking the necessary steps to discover the truth about your gender. Everyone deserves to be happy with who they are, and for transgender women, there are concrete, actionable steps you can take to get there.

If you or a friend is looking to explore this significant part of themselves, read on for some helpful information.

What is Feminizing Therapy?

Feminizing hormone therapy involves pills, creams, and other products that contain elements that trigger a hormonal reaction in your body. This hormonal reaction can enhance female secondary sex characteristics (breasts, hair, skin.)

If you are a transgender woman, Transfemme® feminizing hormone modulation therapy can make you look and feel like a woman. This is because your body, from head to toe, matches the gender you identify as. (This is why feminizing hormone therapy is also referred to as gender-affirming hormone therapy.)

Feminizing hormone therapy includes different types of medication. The two most common are testosterone blockers and estrogen boosters. Human bodies typically have certain levels of testosterone and estrogen (males have more testosterone, females have more estrogen.) Transfemme® feminizing hormone therapy changes your hormone levels such that your body’s estrogen levels get a boost as you aromatize your testosterone into estrogen.

It’s important to note that a “full” feminizing hormone therapy is not required of all transgender women. Likewise, you do not have to “pass” as a woman to live comfortably as a transgender woman, a sissy, or a T-girl.

Some transgender women opt only for breast enhancement pills, which soften their skin and improve their hair. Some make it a goal to transform their whole bodies to look and perform as women in society but still do not decide to undergo sexual reassignment surgery. There’s no one way to live a transgender life – all are welcome and celebrated.

Benefits of Feminization

Relieves gender dysphoria

Gender dysphoria refers to the stress that one feels as they cope with the reality that their appearance doesn’t match the gender that they identify as. With feminizing therapy, your physical attributes can match the gender you feel you are, which can resolve any emotional conflict you feel around that.

Reduces distress

On that same note, emotional conflict can lead to much other related stress. It can affect your self-esteem, how you behave around or interact with others, how you are around your partner or family, and more. For example, making your appearance match your gender identity can help you have a stronger sense of self.

Improves sexual satisfaction

When you’re more self-assured and can perform as the gender, you truly identify as you’re better able to communicate your sexual wants and needs with your partner. From identifying certain physical limitations to exploring kinks and fantasies, sex becomes a more liberating experience.

Feminization improves the overall quality of life.

You deserve to live as the woman you are. Your friends at Transfemme can help you feminize and be the woman you are outwardly. So check out our products today; we have been assisting transwomen since 1996! For inquiries, call us at 1-877-552-3033 or message us at 1-647-867-6180.

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What is Forced Feminization?

The world of BDSM is truly a world of pure imagination. People discover how colorful their sexual fantasies are and just what the magic of experiencing them is like.

More than that, BDSM can sometimes be a tool for people to get to know themselves better in the gender or sexual orientation sense. Again, this is a benefit that the kink forced feminization can offer. Learn more about it here.

What is Forced Feminization?

In BDSM, forced feminization happens when a dominant partner, whether male or female, makes their male submissive play a feminine role. It is also known as “sissification,” It sometimes involves “sissy training,” where the male submissive is trained to act female during play.
Forced feminization is a more fetish-based level of cross-dressing. This means that males who consent to forced feminization during BDSM play do not necessarily identify as transgender outside the BDSM act or the bedroom. Still, they do so to explore a sexual fetish with their partner.

Mental health considerations with transgender and gender

There are several reasons why a male-identified person would want to try forced feminization. First, as a fetish, something is exciting about performing as a submissive female and surrendering to your dominant partner – it can be a way of releasing control. Plus, sexual fantasies are usually challenging to explain; forced feminization can feel liberating when done with a trusted partner!
In terms of mental health, forced feminization can become a way for a male-identified person to have an outlet for femininity, without the shame or guilt that usually occurs when men act like women. They can be vulnerable and gentle, which is especially important for males who feel they are expected to be strong and masculine all the time.
Male-identified people can later discover that they are transgender because of this kink. It’s an intimate and healthy way to find one’s true gender identity. However, not all men who enjoy forced femme are transgender; for some men, it simply is a kink they like to do with their partner. Nevertheless, all are healthy, enjoyable ways to explore one’s sexuality.

The Feminization of Psychotherapy

The term “feminization of psychotherapy” refers to the increasing number of women who have chosen psychotherapy as their profession. This is welcome news for couples who enjoy forced feminization as a kink.

Lucky for them, there are plenty of female sex therapists they can turn to talk openly about forced feminization or BDSM. Forced feminization typically becomes a concern only when the male-identified submissive partner experiences confusion with gender identity. With a female sex therapist, male-identified submissive partners can feel safe when bringing up any issues they encounter as they explore their feminine side.

Need help exploring your feminine side? Your friends at Transfemme can help.

Whether you’re looking to get softer skin, other female body attributes, or fully transform into a woman, Transfemme is here to support you in your forced feminization journey. So check out our products today! For inquiries, call us at 1-877-552-3033 or message us on WhatsApp at

Get Our MTF Information Package Today!

✅ Learn about safe and effective gender-affirming products.

🌱 Get tips on self-care and confidence-building.

🔬 Discover the science behind Transfemme’s trusted solutions.

🎁 Receive a discount code just for signing up!

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Male to Female Transformation: Best done naturally

Male to Female Transformation: Best done naturally

When it comes to MTF transition, going the natural route is always the best way to go, and male breast enlargement pills are what you will need along with that journey. So why are male breast enhancement and male-to-female transformation in general better when done through this method? Here are a few reasons. 

You already have a lot of feminine in you anyway.   

Our physical bodies are composed both of testosterone and estrogen. So what makes a man appear “male” or a woman appear “female” is due primarily to the levels of testosterone or estrogen in their bodies. What male breast enhancement pills can do is bring out more of that estrogen through a process called aromatization. 

These pills help you take advantage of the fact that your natural body can transform itself into the more feminine version of you — whether you want softer features or you’re looking to transform into a woman fully. How amazing is that?

You experience a total body transformation.    

When we say male to female transformation, we mean the “transformation” part. With the extra boost in estrogen you get through our Transfemme pills and Bountiful Breast creams, your whole body benefits: you get smoother skin, less hair growth, rounder breasts or hips, and more.

Of course, how much your body would transform depends on what program you would like to be on: partial or complete feminization. (We’re available for consultation if you need any more information about these programs.)

Natural is always more attractive. 

Here at Transfemme, one of our main motivations for creating our products is that is we did not want to undergo breast implant surgery. We understand and believe that getting breast implants is usually a bad idea. But, first, for the apparent reason that breast implants can look too fake — we wanted breasts that seem as though they have been a part of our bodies forever, not something that was “put on.” Second, we knew male breast enlargement was possible, and we wanted to pursue that.

That is why we are here to share with you our knowledge and offer our support. From offering you the best package of male breast enlargement pills and cream to making ourselves available for consultation, we’ve got you.

You will transform over time.

MTF transition may take a while, but that in itself is where the joy is! The keyword there is “transition,” meaning you will experience physical changes over time. Ask any trans sister — there is nothing like the satisfaction of observing your body change through time and realizing later on how far you’ve gone. 

Are you interested in our male-to-female transformation programs? Check out our products today! For inquiries, call us at 1-877-552-3033 or message us at 1-647-867-6180.

Full Body Male to Female Hormones Transformation Pictures

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Estrogen Pills for Men

Estrogen Pills for Men

Estrogen can be prescribed by a physician for a male to female transitioning and after sex reassignment surgery. Not all men want to undergo the rigorous requirements and invasion of privacy to acquire estrogen pills. The main non-prescription estrogen pill for men is Transfemme®.

Where can I buy male to female hormones?

Transfemme® male to female hormones in pill and cream forms are available online on this website. Transfemme is a completely natural system to feminize the male body to varying degrees depending on which products you use and the dosages. We recommend calling one of our advisors on our Customer Success Team at 877-552-3033 or email us at customersuccessteam@transfemme.com

Male to Female Hormone Pills at Walmart

Walmart sells herbal pills that cause an insignificant feminization effect, these are not real male to female hormones. If you are thinking about buying male to female hormone pills at Walmart you need to understand that an herb does not stop testosterone, you will still have testosterone which is going to keep your body masculine. Walmart is not equipped or interested in helping you transition or grow breasts. Putting a small amount of phytoestrogen in your body is not going to give you the results you are looking for.

What hormones are used for Male to Female Transition?

Lupron, spironolactone, bicalutamide, flutamide, finasteride are normally prescribed hormones for a male to female transition. Lupron is given intramuscularly every sixty days to block total testosterone levels. This is an expensive treatment and insurance rarely pays for this. Finasteride reverses male pattern baldness because it blocks dihydrotestosterone (DHT), it does not block overall testosterone. We recommend using Transfemme® to cause your testosterone to aromatize into estrogen naturally to create MTF estradiol. What happens when a man takes female hormones? Female hormones can cause side effects in men, before taking prescription drugs you should carefully decide if these risks are acceptable and how much risk you may have based on age, weight, family history. The effects of estrogen on the male body are significant and the benefits should outweigh the risks when considering altering your hormones with prescription hormones.

What happens when a man takes female hormones?

The risks include high blood pressure, high blood sugar, inflammation, higher C-Reactive Protein, high cholesterol, type 2 diabetes, and weight gain, all of which can cause heart disease. Excessive prolactin or the formation of noncancerous tumors in your pituitary gland that causes prolactinoma. Blood clots called deep vein thrombosis or a pulmonary embolism, blood clots can also cause strokes.

Infertility, decreased libido, erectile dysfunction, gallstones, elevated liver enzymes. Once your testosterone levels decrease your sperm count will decrease and you will not be able to have children. Many men using hormones for a male to female transition are happy to have decreased erectile function, shrinking genitals they can tuck, and smaller testicles. Drugs have side effects, think carefully before you decide to do this. There are safer ways to still have great results without resorting to more extreme measures. We have helped thousands of pre- and post-op transwomen and men seeking partial feminization since 1996.

Transfemme® feminizing hormone therapy results vary in a time frame, generally, you will see changes anywhere from three weeks to three months. Everyone’s timeline looks slightly different. You can expect the following to occur: Areola enlargement: This usually occurs in the first month and can take three months. Customers usually report this is one of the first changes they see. Breast development: Will occur after one to six months of using Transfemme®. Our customers report seeing results for years. Female body fat distribution: This will start in two to six months after starting Transfemme®. Expect female body contouring to continue for five years. Testicular atrophy: You should expect to see this in three to six months of using Transfemme®. Atrophy will continue over two to three years! Decreased libido: This will begin one to three months after starting treatment. The maximum effect will occur within one to two years. Decreased spontaneous erections: This will begin one to three months after treatment. The maximum effect will occur within three to six months. Decreased facial hair: Our customers report seeing this in the first six months and continuing for two years.

“While taking Estrogen pills for men can cause your testicles and penis to shrink Transfemme® causes your body to aromatize your own testosterone into your own estrogen.”

Questions and Answers about Estrogen Pills for Men:

  1. Will taking estrogen change my voice? No, to alter your voice you need surgery and voice lessons.
  2. Will male to female hormones change my body structure? Unfortunately no, your body will not decrease in size. Are there any Clinical Trials for the effects of estrogen on the male body?
  3. Are there any Clinical Trials for the effects of estrogen on the male body? Yes, there is a clinical trial currently open at the Mayo Clinic. Here is a link to the trial. A Study to Evaluate The Effect of Transgender Hormone Therapy on Adipose Tissue Biology and Distribution https://www.mayo.edu/research/clinical-trials/cls-20454329

In transgender women or trans feminine people (MTF), the most commonly used medications are estrogens and anti-androgens. Administration of estrogen(via oral, sublingual, transdermal, intramuscular, or subcutaneous routes) lower serum testosterone levels, raise serum estradiol levels, and results in the development of typical female secondary sex characteristics including: breast growth, softer skin, decreased muscle mass, and female-pattern fat distribution. 

These effects are largely reversible. Estrogen can also cause testicular and penile atrophy (ultimately resulting in potential erectile dysfunction and infertility). Some trans women also describe changes in emotions (e.g., more tearful) as well as decreased libido. Adverse effects can include increased risk for thrombosis, elevations in blood pressure, elevations in prolactin (rarely including the development of a prolactinoma), migraines, elevations in transaminases, and effects on fertility (although estrogen is not an effective contraceptive). 

Estrogens will NOT heighten voice pitch, decrease facial hair, change facial bone structure, or reverse male-pattern baldness. Other methodologies would need to be employed (e.g., voice training, electrolysis or laser hair removal, facial feminization surgery, hair restoration, etc).

Anti-androgens (i.e. spironolactone, bicalutamide, flutamide, finasteride) are also commonly used in trans women who have not had an orchiectomy. These medications block the effects of testosterone, resulting in decreased erectile function and allowing estrogen to develop typical female secondary sex characteristics. Finasteride, however, specifically targets dihydrotestosterone (DHT), not testosterone, so it is not as effective at lowering total testosterone levels.

GnRH Agonists (i.e. Lupron) could also be used instead of Anti-Androgens to block endogenous testosterone production. Lupron is typically given intramuscularly every couple of months and is very effective at blocking total testosterone levels. However, it can be difficult to obtain insurance coverage for it, and is otherwise fairly expensive out of pocket.

Progesterones activate the androgen receptors slightly, so may be used to improve libido and mood. in some cases, it may be indicated to maximize breast growth, though this is likely happening via weight gain. Of note, some studies show a possible increased risk for VTE, cardiovascular disease and/or breast cancer with use.