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Ingredients:

The tuberous root of P. mirifica contains a high number of potent phytoestrogens, including isoflavones (daidzein, daidzin, genistein, genistin, and puerarin), lignans, and coumestans [18]. Traditionally, P. mirifica has been consumed for various purposes, such as an anti-wrinkle agent, appetite promoter, hair-blackening agent, memory enhancer, and longevity booster [19,20]. It exerts an oestrogenic effect on hormone-sensitive tissues and organs, contributing to its antioxidant properties [17], prevention of bone loss [21,22], and prevention of breast cancer in rats [23]. Moreover, studies have demonstrated its ability to downregulate the expression of interleukin-6, androgen receptor, and estrogen receptors in prostatic tissue, leading to anti-inflammatory effects that ameliorate BPH [24]. As BPH is primarily driven by the growth of prostatic tissue in response to the presence of androgens, particularly DHT, which bind to and activate the androgen receptor in the prostate gland, we hypothesize that P. mirifica exhibits inhibitory effects on 5α-reductase. This, in turn, will result in reduced dihydrotestosterone (DHT) production and decreased proliferation of prostatic epithelial and stromal cells, leading to mitigation of benign prostatic hyperplasia (BPH) development in the testosterone-induced BPH rat model. Therefore, the objective of the current study is to evaluate the inhibitory effect of 5α-reductase by P. mirifica and its histomorphological effects in a rat model of testosterone-induced BPH. https://medic.upm.edu.my/upload/dokumen/2023100415...

Many customers have said that our Godiva TF Booster pills have aided in a healthy prostate while minimizing prostate swelling!

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